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TIC in globally ischemic hearts from control and transgenic animals. Control and transgenic (Trans) hearts were either untreated (n = 11 and 13, respectively) or pretreated with 50 μM 8-(p-sulfophenyl)theophylline (Con+8-SPT and Trans+8-SPT, n = 15 and 6, respectively). Additionally, control hearts were treated with N6-cyclopentyladenosine (Con+CPA, n = 6). Values shown are means ± SEM. ∗, P < 0.05 different from control hearts; †, P < 0.05 less than Trans hearts.
