Table 3.
PCK
|
Normal
|
|||||
---|---|---|---|---|---|---|
Fetal liver | Adult liver
|
Fetal liver | Adult liver | |||
C-type | F- type | |||||
Epithelial markers | Pan-CK | ++ | ++ | + | ++ | ++ |
CK7 | ++ | ++ | + | ++ | ++ | |
CK19 | ++ | ++ | + | ++ | ++ | |
E-cadherin | − | + | + | − | + | |
Mesenchymal markers | Vimentin | + | − | ++∼+ | + | − |
Desmin | − | − | − | − | − | |
α-SMA | − | − | − | − | − | |
N-cadherin | − | − | + ∼− | − | − | |
Fibronectin | − | − | ++ ∼+ | − | − |
++, strongly positive; +, moderate to weakly positive; −, negative. CK, cytokeratin; SMA, smooth muscle actin.