Table 6.
Individual Fold Differences in IL-6 and SOCS-3 Gene Expression
| Group | Animal no. | IL-6*
|
SOCS-3*
|
||
|---|---|---|---|---|---|
| Colon | Jejunum | Colon | Jejunum | ||
| SIV-infected with diarrhea (group 1) | AJ82 | 11 | 27 | 17 | 39 |
| DD88 | 46 | 696 | 31 | 135 | |
| CI65 | 16 | 72 | 28 | 42 | |
| L441 | 5 | 3 | 22 | 4 | |
| H405 | 77 | 12 | 12 | 13 | |
| V205 | 14 | 17 | 12 | 32 | |
| AT81 | 482 | 71 | 80 | 121 | |
| AT56 | 107 | 43 | 98 | 153 | |
| DT56 | 24 | NA | 52 | NA | |
| DI28 | 7 | 4 | 21 | 7 | |
| Non-SIV infected with diarrhea (group 2) | EI90 | 27 | NA | 38 | NA |
| EL45 | 26 | NA | 20 | NA | |
| EC49 | 28 | NA | 34 | NA | |
| EB12 | 55 | NA | 57 | NA | |
| EM41 | 8 | 2 | 8 | 3 | |
| EL71 | 134 | 1 | 97 | 7 | |
| EB27 | 21 | 12 | 20 | 25 | |
| DJ15 | 16 | 2 | 52 | 4 | |
| CT77 | 12 | 21 | 30 | 25 | |
| EJ54 | 51 | 3 | 24 | 29 | |
| Control animals (group 3) | BV52 | 2 | 6 | 2 | 13 |
| CB98 | 5 | 3 | 7 | 4 | |
| CF33 | 9 | 8 | 3 | 7 | |
| M302 | 2 | 2 | 2 | 1 | |
| CC96 | 2 | 2 | 1 | 2 | |
| R842 | 1 | 2 | 4 | 3 | |
*
Fold changes in the relative gene expression were determined by evaluating the expression, 2−DΔ CT.
Colon and jejunum specimens from EH70 (group 3) were not used for qRT-PCR analysis.
NA, not applicable.