Table 2 Biallelic results for four markers of iNOS testing null hypotheses of no linkage and no association (family based association test, additive model) in 230 Indian families with probands with asthma.

Allele	Repeat size	Allele frequency	Informative families (n)	z Score	p Value*
−2.5 kb CCTTT repeat (M1)
1 (176 bp)	9	0.042	32	0.926	0.355
2 (181 bp)	10	0.166	92	–0.612	0.541
3 (186 bp)	11	0.162	89	0.476	0.634
4 (191 bp)	12	0.192	108	–1.273	0.203
5 (196 bp)	13	0.153	96	0.219	0.827
6 (201 bp)	14	0.132	80	0.722	0.470
7 (206 bp)	15	0.107	61	0.663	0.508
8 (211 bp)	16	0.022	19	–0.539	0.590
9 (216 bp)	17	0.012	10	0.577	0.564
10 (221 bp)	18	0.005	2	–	–
Intron 2 GT repeat (M2)
1 (215 bp)	19	0.032	24	–1.095	0.273
2 (217 bp)	20	0.146	70	–0.826	0.409
3 (219 bp)	21	0.522	149	2.288	0.022
4 (221 bp)	22	0.245	104	–1.422	0.155
5 (223 bp)	23	0.03	19	–0.888	0.374
6 (225 bp)	24	0.014	10	0.302	0.763
7 (229 bp)	26	0.011	2	–	–
Intron 4 GT repeat (M3)
1 (343 bp)	13	0.213	89	–0.926	0.354
2 (345 bp)	14	0.007	7	–	–
3 (347 bp)	15	0.406	142	2.759	0.006
4 (349 bp)	16	0.166	82	–0.403	0.687
5 (351 bp)	17	0.011	9	–	–
6 (353 bp)	18	0.154	88	–2.001	0.045
7 (355 bp)	19	0.026	15	0.19	0.849
8 (357 bp)	20	0.016	10	–0.632	0.527
9 (339 bp)	11	0.002	1	–	–
Intron 5 CA repeat (M4)
1 (323 bp)	14	0.238	65	1.73	0.08
2 (325 bp)	15	0.144	60	–1.91	0.06
3 (327 bp)	16	0.207	69	–1.33	0.18
4 (329 bp)	17	0.087	28	–0.82	0.41
5 (331 bp)	18	0.013	8	–	–
6 (333 bp)	19	0.027	11	2.32	0.02
7 (335 bp)	20	0.046	19	2.12	0.03
8 (337 bp)	21	0.059	30	–0.26	0.79
9 (339 bp)	22	0.148	66	0.40	0.69
10 (341 bp)	23	0.029	10	–1.27	0.21
11 (343 bp)	24	0.003	1	—	—

*p Values are nominal and not corrected for the multiple testing.