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. 2007 May 9;66(11):1518–1524. doi: 10.1136/ard.2006.064717

Table 2 Long‐term outcome after median 9 years in comparison with trial data of 61 juvenile idiopathic arthritis patients who participated in a randomised placebo‐controlled sulfasalazine trial13*.

Variable Trial baseline End of trial (24 weeks) Follow‐up (median 9 years) Differences between end of trial and follow‐up p value
General assessments
 Active joints (range 0 to 71) 5 (3 to 11) 2 (1 to 7) 2 (0 to 6) NS
 Limited joints (range 0 to 67)† 4 (1 to 7) 2 (1 to 5) 5 (2 to 12) <0.001
 Physician's score of disease activity (range 0 to 5)‡ 3 (3 to 4) 2 (1 to 3) 2 (1 to 3) NS
 Erythrocyte sedimentation rate mm/h 27 (11 to 43) 11 (6 to 22) 8 (5 to 22) NS
 C‐reactive protein mg/l 6 (1 to 29) 2 (1 to 11) 2 (1 to 6) NS
No. (%) of patients with
 No active joints 0 14 (23%) 16 (26%) NS
 No limited joints 6 (10%) 9 (15%) 6 (10%) NS
 >4 active joints 36 (59%) 20 (33%) 18 (30%) NS
 >4 limited joints 26 (43%) 18 (30%) 33 (54%) <0.001

*Values are given in median and interquartile range (IQR 25 to 75%) or number and percentage as indicated; †limited joints = joints with limitation in range of motion;17 ‡PGAS: 0 = none; 1+ = very low; 2+ = low; 3+ = moderate; 4+ = active; 5+ = very active.