Table 3 haplotype block and haplotype‐based association analysis in the genomic region covering the TNFα locus.
| Haplotype block | Haplotype frequency | χ2 | p Value | ||
|---|---|---|---|---|---|
| Haplotype | Sequence | AS | Control | ||
| A | ATCACCG | 0.18 | 0.21 | 0.28 | 0.60 |
| B | GATCT*TC | 0.22 | 0.12 | 6.59 | 0.010 |
| C | AATCCCC | 0.09 | 0.11 | 0.55 | 0.46 |
| D | AATCCTC | 0.09 | 0.08 | 0.41 | 0.52 |
| E | ATCACCC | 0.06 | 0.09 | 0.13 | 0.71 |
| F | GATCCTC | 0.07 | 0.08 | 0.87 | 0.35 |
| G | AATCTTC | 0.04 | 0.03 | 0.36 | 0.55 |
*–850T Allele.
Haplotypes A–G include seven SNPs spanning a 58‐kb region.
Significant p values are in bold.