Table 2 HLA‐DRB1 serotype frequencies observed in patients with RA and control subjects .
| Serotype | BRASS | Control | ||||
|---|---|---|---|---|---|---|
| n (%) | SE, n (%) | D70, n (%) | n (%) | SE, n (%) | D70, n (%) | |
| DR1 | 180 (13.1) | 168 (93.3) | 12 (6.7) | 114 (11.8) | 102 (89.5) | 12 (10.5) |
| DR2 (15) | 148 (10.7) | 119 (12.3) | ||||
| DR2 (16) | 22 (1.6) | 22 (100) | 12 (1.2) | 12 (100) | ||
| DR3 | 147 (10.7) | 121 (12.6) | ||||
| DR4 | 479 (34.8) | 428 (89.4) | 24 (5) | 168 (17.4) | 138 (82.1) | 10 (6) |
| DR7 | 100 (7.3) | 100 (100) | 127 (13.2) | 127 (100) | ||
| DR8 | 25 (1.8) | 25 (100) | 22 (2.3) | 22 (100) | ||
| DR9 | 12 (0.9) | 5 (0.5) | ||||
| DR10 | 23 (1.7) | 23 (100) | 7 (0.7) | 7 (100) | ||
| DR11/DR13 | 214 (15.5) | 214 (100) | 241 (25) | 241 (100) | ||
| DR12 | 6 (0.4) | 6 (100) | 3 (0.3) | 3 (100) | ||
| DR14 | 22 (1.6) | 2 (9.1) | 25 (2.6) | 1 (4) | ||
| Totals | 1378 | 621 (45.1) | 403 (29.2) | 964 | 248 (25.7) | 427 (44.3) |
BRASS, Brigham and Women's Rheumatoid Arthritis Sequential Study; HLA, human leucocyte antigen; RA, rheumatoid arthritis; SE, shared eipitope.