Table 1 Patient demographics at baseline.
| Cases n = 43 | Control n = 43 | Cohort* n = 630 | p value | ||
|---|---|---|---|---|---|
| Case vs control | Case vs cohort | ||||
| RA, n (%) | 32 (74) | 30 (70) | 437 (69) | ||
| Other rheumatic diagnoses, n (%) | 11 (26) | 13 (30)† | 129 (20)‡ | ||
| Female, n (%) | 33 (77) | 33 (77) | 437 (69) | ||
| Median age at first infusion, years (range) | 57 (21–84) | 53 (18–81) | 54 (17–87) | ||
| Disease duration, years | 13.5 (1.9) | 10.6 (1.3) | 11 (0.5) | 0.279 | 0.359 |
| ESR, mm | 42.2 (4.48) | 33.4 (3.7) | 34.5 (1.12) | 0.125 | 0.066 |
| CRP, mg/l | 39.0 (5.5) | 37.9 (4.9) | 35.2 (1.8) | 0.878 | 0.569 |
| DAS28 | 5.52 (0.24) | 5.75 (0.22) | 5.54 (0.06) | 0.793 | 0.550 |
| HAQ, baseline median (IQR§) | 1.75 (1.13–2.25) | 1.5 (0.63–2.25) | 1.38 (0.88–1.88) | 0.373 | 0.054 |
| No. of failed DMARDs | 3.7 (0.3) | 2.6 (0.2) | 3.8 (0.1) | 0.012 | 0.690 |
Data are given as mean (SEM) unless otherwise stated.
*Including controls; †of whom two controls with JCA were matched with cases with RA; ‡data missing for patients registered at private ward facilities; §IQR: interquartile range.