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. 1982 Dec 1;95(3):771–780. doi: 10.1083/jcb.95.3.771

Participation of calmodulin in immunoglobulin capping

PMCID: PMC2112913  PMID: 6185505

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Selected References

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  1. BUTCHER R. W., SUTHERLAND E. W. Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. J Biol Chem. 1962 Apr;237:1244–1250. [PubMed] [Google Scholar]
  2. Bennett V. Immunoreactive forms of human erythrocyte ankyrin are present in diverse cells and tissues. Nature. 1979 Oct 18;281(5732):597–599. doi: 10.1038/281597a0. [DOI] [PubMed] [Google Scholar]
  3. Bourguignon L. Y., Balazovich K. Effect of the antidepressant drug-Stelazine on lymphocyte capping. Cell Biol Int Rep. 1980 Oct;4(10):947–952. doi: 10.1016/0309-1651(80)90197-6. [DOI] [PubMed] [Google Scholar]
  4. Branton D., Cohen C. M., Tyler J. Interaction of cytoskeletal proteins on the human erythrocyte membrane. Cell. 1981 Apr;24(1):24–32. doi: 10.1016/0092-8674(81)90497-9. [DOI] [PubMed] [Google Scholar]
  5. Braun J., Fujiwara K., Pollard T. D., Unanue E. R. Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin. J Cell Biol. 1978 Nov;79(2 Pt 1):409–418. doi: 10.1083/jcb.79.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Braun J., Fujiwara K., Pollard T. D., Unanue E. R. Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. II. Contrasting effects of local anesthetics and a calcium ionophore. J Cell Biol. 1978 Nov;79(2 Pt 1):419–426. doi: 10.1083/jcb.79.2.419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Braun J., Sha'afi R. I., Unanue E. R. Crosslinking by ligands to surface immunoglobulin triggers mobilization of intracellular 45Ca2+ in B lymphocytes. J Cell Biol. 1979 Sep;82(3):755–766. doi: 10.1083/jcb.82.3.755. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Charbonneau H., Cormier M. J. Purification of plant calmodulin by fluphenazine-Sepharose affinity chromatography. Biochem Biophys Res Commun. 1979 Oct 12;90(3):1039–1047. doi: 10.1016/0006-291x(79)91931-4. [DOI] [PubMed] [Google Scholar]
  9. Cheung W. Y. Calmodulin plays a pivotal role in cellular regulation. Science. 1980 Jan 4;207(4426):19–27. doi: 10.1126/science.6243188. [DOI] [PubMed] [Google Scholar]
  10. Conn P. M., Chafouleas J. G., Rogers D., Means A. R. Gonadotropin releasing hormone stimulates calmodulin redistribution in rat pituitary. Nature. 1981 Jul 16;292(5820):264–265. doi: 10.1038/292264a0. [DOI] [PubMed] [Google Scholar]
  11. De Petris S. Inhibition and reversal of capping by cytochalasin B, vinblastine and colchicine. Nature. 1974 Jul 5;250(461):54–56. doi: 10.1038/250054a0. [DOI] [PubMed] [Google Scholar]
  12. Dedman J. R., Welsh M. J., Means A. R. Ca2+-dependent regulator. Production and characterization of a monospecific antibody. J Biol Chem. 1978 Oct 25;253(20):7515–7521. [PubMed] [Google Scholar]
  13. Deuticke B. Transformation and restoration of biconcave shape of human erythrocytes induced by amphiphilic agents and changes of ionic environment. Biochim Biophys Acta. 1968 Dec 10;163(4):494–500. doi: 10.1016/0005-2736(68)90078-3. [DOI] [PubMed] [Google Scholar]
  14. Eibl H., Lands W. E. A new, sensitive determination of phosphate. Anal Biochem. 1969 Jul;30(1):51–57. doi: 10.1016/0003-2697(69)90372-8. [DOI] [PubMed] [Google Scholar]
  15. Fairbanks G., Steck T. L., Wallach D. F. Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. Biochemistry. 1971 Jun 22;10(13):2606–2617. doi: 10.1021/bi00789a030. [DOI] [PubMed] [Google Scholar]
  16. Flanagan J., Koch G. L. Cross-linked surface Ig attaches to actin. Nature. 1978 May 25;273(5660):278–281. doi: 10.1038/273278a0. [DOI] [PubMed] [Google Scholar]
  17. Fujiwara K., Pollard T. D. Fluorescent antibody localization of myosin in the cytoplasm, cleavage furrow, and mitotic spindle of human cells. J Cell Biol. 1976 Dec;71(3):848–875. doi: 10.1083/jcb.71.3.848. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Gabbiani G., Chaponnier C., Zumbe A., Vassalli P. Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature. 1977 Oct 20;269(5630):697–698. doi: 10.1038/269697a0. [DOI] [PubMed] [Google Scholar]
  19. Geiger B., Singer S. J. The participation of alpha-actinin in the capping of cell membrane components. Cell. 1979 Jan;16(1):213–222. doi: 10.1016/0092-8674(79)90202-2. [DOI] [PubMed] [Google Scholar]
  20. Gietzen K., Wüthrich A., Bader H. R 24571: a new powerful inhibitor of red blood cell Ca++-transport ATPase and of calmodulin-regulated functions. Biochem Biophys Res Commun. 1981 Jul 30;101(2):418–425. doi: 10.1016/0006-291x(81)91276-6. [DOI] [PubMed] [Google Scholar]
  21. Guerriero V., Jr, Rowley D. R., Means A. R. Production and characterization of an antibody to myosin light chain kinase and intracellular localization of the enzyme. Cell. 1981 Dec;27(3 Pt 2):449–458. doi: 10.1016/0092-8674(81)90386-x. [DOI] [PubMed] [Google Scholar]
  22. Head J. F., Perry S. V. The interaction of the calcium-binding protein (troponin C) with bivalent cations and the inhibitory protein (troponin I). Biochem J. 1974 Feb;137(2):145–154. doi: 10.1042/bj1370145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Hidaka H., Sasaki Y., Tanaka T., Endo T., Ohno S., Fujii Y., Nagata T. N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc Natl Acad Sci U S A. 1981 Jul;78(7):4354–4357. doi: 10.1073/pnas.78.7.4354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Hidaka H., Yamaki T., Totsuka T., Asano M. Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. Mol Pharmacol. 1979 Jan;15(1):49–59. [PubMed] [Google Scholar]
  25. Hoover R. L., Fujiwara K., Klausner R. D., Bhalla D. K., Tucker R., Karnovsky M. J. Effects of free fatty acids on the organization of cytoskeletal elements in lymphocytes. Mol Cell Biol. 1981 Oct;1(10):939–948. doi: 10.1128/mcb.1.10.939. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Kao K. J., Sommer J. R., Pizzo S. V. Modulation of platelet shape and membrane receptor binding by Ca2+-calmodulin complex. Nature. 1981 Jul 2;292(5818):82–84. doi: 10.1038/292082a0. [DOI] [PubMed] [Google Scholar]
  27. Klausner R. D., Kleinfeld A. M., Hoover R. L., Karnovsky M. J. Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis. J Biol Chem. 1980 Feb 25;255(4):1286–1295. [PubMed] [Google Scholar]
  28. Kobayashi R., Tawata M., Hidaka H. Ca2+ regulated modulator protein interacting agents: inhibition of Ca2+-Mg2+-ATPase of human erythrocyte ghost. Biochem Biophys Res Commun. 1979 Jun 13;88(3):1037–1045. doi: 10.1016/0006-291x(79)91513-4. [DOI] [PubMed] [Google Scholar]
  29. Laemmli U. K., Favre M. Maturation of the head of bacteriophage T4. I. DNA packaging events. J Mol Biol. 1973 Nov 15;80(4):575–599. doi: 10.1016/0022-2836(73)90198-8. [DOI] [PubMed] [Google Scholar]
  30. Levin R. M., Weiss B. Mechanism by which psychotropic drugs inhibit adenosine cyclic 3',5'-monophosphate phosphodiesterase of brain. Mol Pharmacol. 1976 Jul;12(4):581–589. [PubMed] [Google Scholar]
  31. Levine J., Willard M. Fodrin: axonally transported polypeptides associated with the internal periphery of many cells. J Cell Biol. 1981 Sep;90(3):631–642. doi: 10.1083/jcb.90.3.631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Loor F., Forni L., Pernis B. The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins. Eur J Immunol. 1972 Jun;2(3):203–212. doi: 10.1002/eji.1830020304. [DOI] [PubMed] [Google Scholar]
  33. Marcum J. M., Dedman J. R., Brinkley B. R., Means A. R. Control of microtubule assembly-disassembly by calcium-dependent regulator protein. Proc Natl Acad Sci U S A. 1978 Aug;75(8):3771–3775. doi: 10.1073/pnas.75.8.3771. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Montecucco C., Ballardin S., Zaccolin G. P., Pozzan T. Effect of local anaesthetics on lymphocyte capping and energy metabolism. Biochem Pharmacol. 1981 Nov 1;30(21):2989–2992. doi: 10.1016/0006-2952(81)90264-1. [DOI] [PubMed] [Google Scholar]
  35. Mooseker M. S., Graves T. A., Wharton K. A., Falco N., Howe C. L. Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells. J Cell Biol. 1980 Dec;87(3 Pt 1):809–822. doi: 10.1083/jcb.87.3.809. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Niggli V., Penniston J. T., Carafoli E. Purification of the (Ca2+-Mg2+)-ATPase from human erythrocyte membranes using a calmodulin affinity column. J Biol Chem. 1979 Oct 25;254(20):9955–9958. [PubMed] [Google Scholar]
  37. Oakley B. R., Kirsch D. R., Morris N. R. A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels. Anal Biochem. 1980 Jul 1;105(2):361–363. doi: 10.1016/0003-2697(80)90470-4. [DOI] [PubMed] [Google Scholar]
  38. Papahadjopoulos D., Jacobson K., Poste G., Shepherd G. Effects of local anesthetics on membrane properties. I. Changes in the fluidity of phospholipid bilayers. Biochim Biophys Acta. 1975 Jul 18;394(4):504–519. doi: 10.1016/0005-2736(75)90137-6. [DOI] [PubMed] [Google Scholar]
  39. Poste G., Papahadjopoulos D., Nicolson G. L. Local anesthetics affect transmembrane cytoskeletal control of mobility and distribution of cell surface receptors. Proc Natl Acad Sci U S A. 1975 Nov;72(11):4430–4434. doi: 10.1073/pnas.72.11.4430. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Prozialeck W. C., Cimino M., Weiss B. Photoaffinity labeling of calmodulin byphenothiazine antipsychotics. Mol Pharmacol. 1981 Mar;19(2):264–269. [PubMed] [Google Scholar]
  41. Ryan G. B., Unanue E. R., Karnovsky M. J. Inhibition of surface capping of macromolecules by local anaesthetics and tranquillisers. Nature. 1974 Jul 5;250(461):56–57. doi: 10.1038/250056a0. [DOI] [PubMed] [Google Scholar]
  42. Salisbury J. L., Condeelis J. S., Maihle N. J., Satir P. Calmodulin localization during capping and receptor-mediated endocytosis. Nature. 1981 Nov 12;294(5837):163–166. doi: 10.1038/294163a0. [DOI] [PubMed] [Google Scholar]
  43. Schreiner G. F., Unanue E. R. Capping and the lymphocyte: models for membrane reorganization. J Immunol. 1977 Nov;119(5):1549–1551. [PubMed] [Google Scholar]
  44. Sobue K., Muramoto Y., Fujita M., Kakiuchi S. Calmodulin-binding protein of erythrocyte cytoskeleton. Biochem Biophys Res Commun. 1981 Jun 16;100(3):1063–1070. doi: 10.1016/0006-291x(81)91931-8. [DOI] [PubMed] [Google Scholar]
  45. Unanue E. R., Karnovsky M. J., Engers H. D. Ligand-induced movement of lymphocyte membrane macromolecules. 3. Relationship between the formation and fate of anti-Ig-surface Ig complexes and cell metabolism. J Exp Med. 1973 Mar 1;137(3):675–689. doi: 10.1084/jem.137.3.675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Unanue E. R., Perkins W. D., Karnovsky M. J. Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography. J Exp Med. 1972 Oct 1;136(4):885–906. doi: 10.1084/jem.136.4.885. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Vincenzi F. F. Calmodulin pharmacology. Cell Calcium. 1981 Aug;2(4):387–409. doi: 10.1016/0143-4160(81)90027-0. [DOI] [PubMed] [Google Scholar]
  48. Volpi M., Sha'afi R. I., Epstein P. M., Andrenyak D. M., Feinstein M. B. Local anesthetics, mepacrine, and propranolol are antagonists of calmodulin. Proc Natl Acad Sci U S A. 1981 Feb;78(2):795–799. doi: 10.1073/pnas.78.2.795. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Wallace R. W., Cheung W. Y. Calmodulin. Production of an antibody in rabbit and development of a radioimmunoassay. J Biol Chem. 1979 Jul 25;254(14):6564–6571. [PubMed] [Google Scholar]
  50. Walsh M. P., Vallet B., Autric F., Demaille J. G. Purification and characterization of bovine cardiac calmodulin-dependent myosin light chain kinase. J Biol Chem. 1979 Dec 10;254(23):12136–12144. [PubMed] [Google Scholar]
  51. Watanabe K., Williams E. F., Law J. S., West W. L. Effects of vinca alkaloids on calcium-calmodulin regulated cyclic adenosine 3' ,5'-monophosphatase phosphodiesterase activity from brain. Biochem Pharmacol. 1981 Feb 15;30(4):335–340. doi: 10.1016/0006-2952(81)90063-0. [DOI] [PubMed] [Google Scholar]
  52. Watterson D. M., Harrelson W. G., Jr, Keller P. M., Sharief F., Vanaman T. C. Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase. J Biol Chem. 1976 Aug 10;251(15):4501–4513. [PubMed] [Google Scholar]
  53. Weiss B., Prozialeck W., Cimino M., Barnette M. S., Wallace T. L. Pharmacological regulation of calmodulin. Ann N Y Acad Sci. 1980;356:319–345. doi: 10.1111/j.1749-6632.1980.tb29621.x. [DOI] [PubMed] [Google Scholar]
  54. Welsh M. J., Dedman J. R., Brinkley B. R., Means A. R. Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. Proc Natl Acad Sci U S A. 1978 Apr;75(4):1867–1871. doi: 10.1073/pnas.75.4.1867. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Woda B. A., Yguerabide J., Feldman J. D. The effect of local anesthetics on the lateral mobility of lymphocyte membrane proteins. Exp Cell Res. 1980 Apr;126(2):327–331. doi: 10.1016/0014-4827(80)90271-2. [DOI] [PubMed] [Google Scholar]
  56. Wood J. G., Wallace R. W., Whitaker J. N., Cheung W. Y. Immunocytochemical localization of calmodulin and a heat-labile calmodulin-binding protein (CaM-BP80) in basal ganglia of mouse brain. J Cell Biol. 1980 Jan;84(1):66–76. doi: 10.1083/jcb.84.1.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Yakara I., Kakimoto-Sameshima F. Microtubule organization of lymphocytes and its modulation by patch and cap formation. Cell. 1978 Sep;15(1):251–259. doi: 10.1016/0092-8674(78)90100-9. [DOI] [PubMed] [Google Scholar]
  58. Young-Karlan B. R., Ashman R. F. Order of events leading to surface immunoglobulin capping: analysis of a transmembrane signal. J Immunol. 1981 Sep;127(3):1177–1181. [PubMed] [Google Scholar]

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