Table 3.

Multiple mutations occurring in one lacI gene from Msh2^−/− thymic lymphomas (A, B, and E) and an Msh2^−/− normal thymus (G)

Tissue	Animal	No. of mutations per lacI gene	Type of mutation, coding sequence	Site of mutation
Thymic lymphoma	A	2	T → A	703
			T → C	726
		4	T → C	451
			T → C	547
			T → C	549
			T → C	552
	B	2	A → G	320
			ΔA	350–352
	E	2	C → G	755
			A → C	858
		2	T → C	87
			T → C	162
Thymus	G	2	C → T	161
			G → A	222