Figure 1.

The amounts of releasable histamine remaining in the peritonea of control (time “0”) and implant-bearing mice. After implantation with PET disks for different periods of time, mice were euthanized and the peritoneal cavity was instilled with cold sterile PBS. Histamine concentrations in cell-free lavage fluids were assayed as described in Materials and Methods. Vertical lines denote ± 1 SD (n = 5 in all cases).