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. 1998 Jul 21;95(15):8858–8863. doi: 10.1073/pnas.95.15.8858

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Copyright © 1998, The National Academy of Sciences

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Histological appearance of skin lesions from K5 E2F1 transgenic mice deficient for p53. (A) SCC from a line 1.0 K5 E2F1, p53^+/− mouse stained with hematoxylin/eosin. (B) SCC from a line 1.0 K5 E2F1, p53^+/− mouse immunostained with E2F1 antisera. (C) BCC from a line 1.0 K5 E2F1, p53^+/− mouse stained with hematoxylin/eosin. (D) The same BCC immunostained with E2F1 antisera. (E) Dysplastic hair follicle from a line 1.1 K5 E2F1, p53^+/− mouse stained with hematoxylin/eosin. (F) The same dysplastic hair follicle immunostained with E2F1 antisera. (All micrographs are at ×20 magnification.)