Table 2.

IGF-I and IGF-II levels in the serum and tumor tissue of nude mice bearing DU-145 human androgen-independent prostate xenografts at the end of the treatment period with GH-RH antagonist MZ-5-156

Treatment group	Serum		Tumor
	IGF-I, ng/ml	IGF-II, ng/ml	IGF-I, pg/100 μg protein	IGF-II, pg/100 μg protein
Control	111.5  ±  6.5	35.1  ±  2.48	331  ±  44.57	1,486 ± 252
MZ-5-156	88.3  ±  6.7*	39.8  ±  4.95	402  ±  77.48	304 ± 196.2*

^*P < 0.05 vs. control.