Figure 2.

Identification of B2 Bradykinin Receptor gene transcription start site(s) and promoter region in Human ASM (A, B) and transcription factor analyses of core HRH1 and BDKRB2 promoter (C). Diagrammatic representation of the BDKRB2 genomic structure including identified exons and transcription start sites (TSS) in Human ASM (A) (Exon 1 5'boundary as described [42]). Number of pCR-4 clones clustering to the two potential transcription start sites (B). Data represents combined data from two Human ASM donors. Relevant transcription factor binding sites identified within the 4 kb of the core promoter of HRH1 and BDKRB2 genes by at least two of the four databases utilised (C).