Table 7.

Recurrence and survival rates with omission of radiotherapy.

Authors	Inclusion age	Number of patients	Local or regional recurrence		Local recurrence		Regional recurrence		Overall survival
Hughes et al [15]	>70	636	L+T	4%					L+T	86%
			L+T+R	1% (P < 0.001)					L+T+R	87% (P = 0.94)
Fyles et al [52]	> 50	769			L+T	7.7%	L+T	2.5%	L+T	93.2%
					L+T+R	0.6% (P < 0.001)	L+T+R	0.5% (p = 0.049	L+T+R	92.8% (p = 0.83)
Gruenberger et al [10]	>60	356			Q+ A ± C ± T	5.4%			Q+ A ± C ± T	82%
					Q+ A ± C ± T + R	5.8%			Q+ A ± C ± T +R	82.7%

L +T : Lumpectomy and Tamoxifen. L+T+R : Lumpectomy, Tamoxifen and whole breast irradiation

Q: Quadrenectomy. A: axillary clearance R: whole breast irradiation C; CMF. T: Tamoxifen