Table 1.
Human | Rat | Mouse | |||||||||||||||
GPCR Family | Full- length | Pseudo- genes | Pseudo- genes (%) | New full- length | New pseudo- genes | Full- length | Pseudo- genes | Partial | Pseudo- genes (%) | New full- length | New pseudo- genes | Full- length | Pseudo- genes | Partial | Pseudo- genes (%) | New1 full- length | New1 pseudo- genes |
Adhesion | 33 | 2 | 6% | 0 | 2 | 26 | 1 | 4 | 3% | 0 | 2 | 30 | 1 | 3% | 0 | 0 | |
Frizzled | 11 | 0 | 0% | 0 | 0 | 10 | 1 | 9% | 0 | 0 | 11 | 0 | 0% | 0 | 0 | ||
Glutamate | 22 | 0 | 0% | 0 | 0 | 22 | 0 | 0% | 0 | 0 | 22 | 0 | 0% | 0 | 0 | ||
-V2R subgroup | 1 | 11 | 92% | 1 | 11 | 108 | 87 | 2 | 45% | 23 | 53 | 111 | 183 | 1 | 62% | 21 | 63 |
Rhodopsin | 284 | 27 | 9% | 0 | 1 | 297 | 7 | 4 | 2% | 5 | 0 | 320 | 23 | 7% | 3 | NA* | |
-OR subgroup | 388 | 479 | 55% | 0 | 12 | 1234 | 552 | 28 | 31% | 1234 | 552 | 1081 | 325 | 1 | 23% | NA* | NA* |
Secretin | 15 | 0 | 0% | 0 | 0 | 15 | 0 | 0% | 0 | 0 | 15 | 0 | 0% | 0 | 0 | ||
Taste2 | 25 | 10 | 29% | 0 | 0 | 35 | 6 | 15% | 0 | 0 | 35 | 5 | 13% | 0 | 0 | ||
Vomeronasal1 | 5 | 53 | 91% | 0 | 53 | 105 | 84 | 44% | 12 | 76 | 145 | 164 | 53% | 17 | 92 | ||
Other GPCRs" | 15 | 1 | 6% | 0 | 1 | 15 | 1 | 14% | 1 | 0 | 13 | 1 | 7% | 1 | 0 | ||
Total | 799 | 583 | 1 | 133 | 1867 | 739 | 38 | 1276 | 759 | 1783 | 702 | 2 | 43 | 247 |
The human, rat and mouse GPCR families; their numbers of full-length, pseudogene and partial members; as well as the number of new members identified in this study. GPCR gene sequences were defined as new if their sequence was not available in a public database annotated as a GPCR. *No figure could not be calculated.