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Figure 1 Simulated (N = 1000) serum exogenous AAT concentrations (g/l) with different intravenous infusion schedules. CminSS (•), expected exogenous minimum AAT concentrations at steady state conditions. Solid line, mean exogenous AAT concentrations. (A) 250 mg/kg/28 days (CminSS = 0.19 g/l); (B) 180 mg/kg/21 days (CminSS = 0.23 g/l); (C) 120 mg/kg/14 days (CminSS = 0.34 g/l); (D) 60 mg/kg/7 days (CminSS = 0.73 g/l). Dashed line, 0.26 g/l.