. 2006 Aug 23;61(12):1059–1064. doi: 10.1136/thx.2005.057943

Table 1 Expected exogenous minimum AAT concentrations at steady state (SS) conditions (C_min^SS) obtained from 1000 simulations expressed as mean, 5th and 95th percentiles. Expected total AAT concentrations (exogenous plus native) are shown in brackets.

Dosage regimen	Mean exogenous AAT C_min^SS	5th percentile	95th percentile
60 mg/kg/7 days	0.73 (0.97)	0.31 (0.55)	1.03 (1.27)
50 mg/kg/7 days	0.61 (0.85)	0.28 (0.52)	1.18 (1.42)
120 mg/kg/14 days	0.34 (0.58)	0.15 (0.40)	0.68 (0.92)
100 mg/kg/14 days	0.28 (0.52)	0.12 (0.36)	0.51 (0.75)
180 mg/kg/21 days	0.23 (0.47)	0.09 (0.33)	0.46 (0.70)
150 mg/kg/21 days	0.19 (0.43)	0.08 (0.32)	0.41 (0.65)
250 mg/kg/28 days	0.19 (0.43)	0.05 (0.29)	0.31 (0.55)

Table 1 Expected exogenous minimum AAT concentrations at steady state (SS) conditions (CminSS) obtained from 1000 simulations expressed as mean, 5th and 95th percentiles. Expected total AAT concentrations (exogenous plus native) are shown in brackets.