Table 6 CL 20% higher than CL reported by Piitulainen et al6.
Dosage regimen | Mean exogenous AAT CminSS | 5th percentile | 95th percentile |
---|---|---|---|
60 mg/kg/7 days | 0.54 (0.78) | 0.23 (0.47) | 1.02 (1.26) |
50 mg/kg/7 days | 0.45 (0.69) | 0.19 (0.43) | 0.85 (1.09) |
120 mg/kg/14 days | 0.21 (0.45) | 0.07 (0.31) | 0.43 (0.67) |
180 mg/kg/21 days | 0.15 (0.39) | 0.06 (0.30) | 0.30 (1.03) |
250 mg/kg/28 days | 0.08 (0.32) | 0.03 (0.27) | 0.17 (0.41) |
Mean total AAT CminSS shown in parentheses.