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Figure 2 Profile of dose distribution for mean inhaled fluticasone requirements over 12 months in 48 patients (conventional group) whose ICS dose was adjusted using a priori guidelines and 46 patients in whom the ICS dose was adjusted on the basis of Feno measurements (FeNO group; cut point equivalent to 35 ppb). There was a highly significant difference between the two groups (p = 0.008).138
