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Figure 1 Triggers of exacerbation. Multiple aetiologies of asthma exacerbation are shown schematically. Virus induced exacerbation results in a neutrophilic infiltrate with increases in interleukin (IL)‐8 and IL‐10, among other cytokines. Allergen induced exacerbation results in an eosinophilic infiltrate with increases in IL‐5, other Th2 cytokines, and IgE. The mechanisms for bacteria induced exacerbation are not known.
