Table 5 Multivariate analysis of 30‐day mortality in patients resected for lung cancer in 1993–8 (n = 1844), with and without Charlson co‐morbidity index (CCI) score.
| No | Without co‐morbidity data | With co‐morbidity data | |||
|---|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | ||
| Sex | 0.022 | 0.039 | |||
| Female | 609 | 1.00 (reference) | 1.00 (reference) | ||
| Male | 1235 | 1.96 (1.10 to 3.48) | 1.84 (1.03 to 3.30) | ||
| Age (years) | <0.001 | <0.001 | |||
| <50 | 191 | 1.00 (reference) | 1.00 (reference) | ||
| 50–59 | 353 | 2.02 (0.62 to 6.53) | 1.82 (0.56 to 5.94) | ||
| 60–69 | 676 | 1.93 (0.64 to 5.82) | 1.63 (0.53 to 5.00) | ||
| 70–79 | 588 | 6.05 (2.07 to 17.68) | 4.91 (1.64 to 14.74) | ||
| 80–89 | 36 | 23.35 (5.74 to 95.08) | 19.71 (4.77 to 81.45) | ||
| Side of resection | 0.009 | 0.012 | |||
| Left | 834 | 1.00 (reference) | 1.00 (reference) | ||
| Right | 1010 | 1.95 (1.18 to 3.23) | 1.91 (1.15 to 3.17) | ||
| Surgical approach | 0.70 | 0.81 | |||
| VATS | 34 | 1.00 (reference) | 1.00 (reference) | ||
| Open thoracotomy | 1810 | 0.67 (0.085 to 5.29) | 0.77 (0.093 to 6.39) | ||
| Surgical procedure | <0.001 | <0.001 | |||
| Upper lobectomy | 597 | 1.00 (reference) | 1.00 (reference) | ||
| Middle lobectomy | 52 | 1.54 (0.31 to 7.59) | 1.78 (0.36 to 8.85) | ||
| Lower lobectomy | 409 | 3.00 (1.36 to 6.64) | 3.05 (1.36 to 6.81) | ||
| Bilobectomy | 173 | 4.33 (1.83 to 10.25) | 4.68 (1.95 to 11.20) | ||
| Pneumonectomy | 506 | 5.90 (2.77 to 12.59) | 6.49 (3.00 to 14.06) | ||
| Sublobar resection | 107 | 0.72 (0.15 to 3.46) | 0.71 (0.15 to 3.44) | ||
| Histopathology type | 0.005 | 0.007 | |||
| Adenocarcinoma | 700 | 1.00 (reference) | 1.00 (reference) | ||
| Squamous cell | 716 | 1.31 (0.73 to 2.34) | 1.34 (0.75 to 2.40) | ||
| Other | 428 | 2.54 (1.39 to 4.63) | 2.52 (1.37 to 4.64) | ||
| Pathological stage | 0.003 | 0.003 | |||
| I | 1196 | 1.00 (reference) | 1.00 (reference) | ||
| II | 440 | 1.36 (0.80 to 2.31) | 1.36 (0.80 to 2.31) | ||
| III | 171 | 1.68 (0.82 to 3.47) | 1.66 (0.80 to 3.45) | ||
| IV | 37 | 6.66 (2.43 to 18.28) | 6.83 (2.48 to 18.82) | ||
| Hospital volume | 0.12 | 0.15 | |||
| <20 | 755 | 1.00 (reference) | 1.00 (reference) | ||
| ⩾20 | 1089 | 0.70 (0.45 to 1.10) | 0.72 (0.46 to 1.12) | ||
| Tumour size (cm) | 0.57 | 0.56 | |||
| ⩽3 | 767 | 1.00 (reference) | 1.00 (reference) | ||
| >3–5 | 608 | 0.72 (0.42 to 1.23) | 0.69 (0.40 to 1.19) | ||
| >5 | 434 | 0.69 (0.39 to 1.23) | 0.73 (0.41 to 1.30) | ||
| Unknown | 35 | – | – | ||
| CCI | 0.024 | ||||
| 0 | 945 | – | 1.00 (reference) | ||
| 1–2 | 779 | – | 1.39 (0.85 to 2.28) | ||
| 3–4 | 107 | – | 2.48 (1.12 to 5.45) | ||
| ⩾5 | 13 | – | 7.68 (1.39 to 42.45) | ||
OR, odds ratio; CI, confidence interval; VATS, video assisted thoracic surgery; CCI, Charlson co‐morbidity index.