Table 1 Characteristics of families of children with asthma.
| Family | Individuals | Former and current smokers* n (%) | Asthma† n (%) | Mean (SD) FEV1, % predicted‡ | Mean (SD) FEV1/FVC, % predicted‡ | Mean (SD) bronchodilator response¶** | ||
|---|---|---|---|---|---|---|---|---|
| Pre‐BD§ | Post‐BD¶ | Pre‐BD§ | Post‐BD¶ | |||||
| 1 | 34 | 8 (23.5) | 12 (35.3) | 96.1 (16.8) | 101.1 (13.5) | 94.5 (8.7) | 97.2 (8.7) | 6.6 (12.1) |
| 2 | 18 | 4 (23.5) | 7 (38.9) | 103.9 (24.0) | 109.2 (27.4) | 97.8 (6.9) | 101.2 (7.0) | 6.1 (10.7) |
| 3 | 224 | 37 (16.5) | 56 (25.1) | 96.6 (14.8) | 100.3 (14.5) | 95.8 (7.0) | 98.7 (7.1) | 4.3 (7.2) |
| 4 | 97 | 17 (17.5) | 16 (16.5) | 102.6 (17.4) | 107.0 (17.0) | 96.9 (8.0) | 99.7 (7.8) | 5.0 (7.3) |
| 5 | 8 | 5 (62.5) | 2 (28.6) | 100.1 (13.2) | 102.5 (13.4) | 98.1 (7.7) | 101.4 (5.5) | 2.6 (6.8) |
| 6 | 107 | 10 (9.4) | 8 (7.5) | 99.7 (16.4) | 102.7 (16.0) | 98.5 (6.7) | 101.0 (5.7) | 3.1 (7.3) |
| 7 | 23 | 9 (39.1) | 5 (21.7) | 103.9 (12.4) | 108.8 (11.4) | 98.1 (5.6) | 101.4 (4.5) | 5.0 (5.3) |
| 8 | 129 | 12 (9.3) | 24 (18.6) | 96.8 (13.9) | 100.0 (13.1) | 96.9 (8.7) | 99.3 (7.5) | 3.4 (7.7) |
| All | 640 | 102 (16.0) | 130 (20.4) | 98.5 (15.8) | 102.3 (15.4) | 96.8 (7.6) | 99.5 (7.2) | 4.2 (7.7) |
FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; BD, bronchodilator.
*n = 638 individuals with complete data on smoking.
†Physician‐diagnosed asthma and wheezing within the past year. n = 637 subjects with complete data.
‡Based on prediction equations for Mexican‐Americans in Hankinson et al.22
§n = 640.
¶n = 624. Sixteen individuals did not have post‐bronchodilator spirometry.
**As a percentage of baseline FEV1 (BDRbase).