Table 2 Absolute bronchodilator responses.
| Healthy (n = 78) | CF (n = 39) | nCLD (n = 49) | Asthma (n = 56) | Wheeze (n = 66) | |
|---|---|---|---|---|---|
| ΔRrs6 (hPa.s/l) | −1.51 (−3.69, −0.17) | −1.46 (−3.18, −0.04) | −2.44 (−4.14, −0.98) | −1.17 (−4.10, 0.58) | −1.28 (−4.03, 0.51) |
| ΔXrs6 (hPa.s/l) | 0.57 (−0.27, 1.66) | 0.86 (−0.16, 2.05) | 1.49 (0.15, 3.05) | 0.84 (−0.21, 2.30) | 0.84 (−0.14, 2.33) |
| ΔRrs8 (hPa.s/l) | −1.44 (−2.73, −0.30) | −1.30 (−3.13, 0.28) | −1.94 (−3.78, −0.54) | −1.09 (−3.39, 0.59) | −1.09 (−3.39, 0.53) |
| ΔXrs8 (hPa.s/l) | 0.75 (−0.04, 1.82) | 0.75 (−0.17, 2.06) | 1.51 (0.47, 2.98) | 0.79 (−0.13, 2.47) | 0.79 (−0.13, 2.47) |
| ΔRrs10 (hPa.s/l) | −1.34 (−2.55, −0.21) | −1.24 (−2.62, 0.30) | −1.76 (−3.03, −0.46) | −0.89 (−2.90, 0.29) | −0.95 (−2.90, 0.24) |
| ΔXrs10 (hPa.s/l) | 0.73 (−0.00, 2.03) | 0.73 (0.00, 1.99) | 1.61 (0.36, 3.08) | 0.67 (−0.12, 2.22) | 0.71 (0.00, 2.14) |
Data shown as median absolute change with bronchodilator (10th, 90th percentiles). Numbers in bold indicate a significant difference compared with the healthy group (p<0.05, multiple linear regression for each group adjusted for covariates).
CF, cystic fibrosis; nCLD, neonatal chronic lung disease; Rrs6, Rrs8, Rrs10, respiratory resistance at 6, 8 and 10 Hz; Xrs6, Xrs8, and Xrs10, respiratory reactance at 6, 8 and 10 Hz.