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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Microbes Infect. 2007 Aug 10;9(12-13):1478–1483. doi: 10.1016/j.micinf.2007.08.002

Figure 3. Survival varies by route of immunization.

Figure 3

A/J mice were immunized with AVA ± 20 ug of CpG ODN and challenged 4 wk later with 20 LD50 of STI spores via the aerosol route. Mice immunized i.p. with AVA + CpG ODN (solid line) were significantly better protected than mice immunized i.p. with AVA alone (dashed line) or i.n. with AVA + CpG ODN (dotted line). Challenge was 100% fatal in unimmunized mice. Data show the percent survival of 10 mice/group compiled by combining results from two independent experiments.