Table 2 Crude and multivariate adjusted odds ratios (OR) for poor outcome at three months (by modified Rankin scale) as predicted by dichotomised initial concentrations (< or ⩾ median) of endothelial cell activation markers (n = 106).
| Variable | Crude OR | Adjusted OR | ||||||
|---|---|---|---|---|---|---|---|---|
| OR | (95% CI) | OR | (95% CI) | |||||
| vWf ⩾94.5 nmol/l | 4.6 | (2.0 to 10.9) | 3.3 | (1.1 to 9.8) | ||||
| vWf propeptide ⩾7.75 nmol/l | 3.2 | (1.4 to 7.3) | 2.1 | (0.8 to 5.6) | ||||
| ED1‐fibronectin ⩾2.25 μg/l | 2.3 | (1.0 to 5.1) | 1.0 | (0.9 to 1.2) | ||||
| sICAM‐1 ⩾401 ng/ml | 1.4 | (0.7 to 3.2) | 1.2 | (0.5 to 3.0) | ||||
| sP‐selectin ⩾92.5 ng/ml | 1.6 | (0.7 to 3.6) | 1.3 | (0.5 to 3.3) | ||||
| sE‐selectin ⩾40.0 ng/ml | 1.1 | (0.5 to 2.4) | 1.0 | (0.4 to 2.7) | ||||
vWf adjusted for: age, WFNS, intracisternal amount of blood, intraventricular amount of blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture, vWf propeptide adjusted for: age, WFNS, intracisternal amount of blood, intraventricular amount of blood, loss of consciousness at the time of aneurysm rupture.
ED1‐fibronectin adjusted for: relevant comorbidity, age, sex, WFNS, amount of intracisternal blood, amount of intraventricular blood, loss of consciousness at the time of aneurysm rupture.
sICAM‐1 adjusted for: age, sex, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture.
sP‐selectin adjusted for: age, WFNS, amount of intracisternal blood, amount of intraventricular blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture.
sE‐selectin adjusted for: age, amount of intracisternal blood, amount of intraventricular blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture.
vWf, von Willebrand factor; WFNS, World Federation of Neurosurgical Societies scale.