Table 1 Demographic and clinical details of patients.
Number of patients included | 811 | |
Seizure type | ||
Generalised seizures | 130 (16%) | |
Focal seizures | 517 (64%) | |
Mixed seizures | 155 (19%) | |
Seizure type unknown | 9 (1%) | |
Epilepsy syndrome | ||
Cryptogenic focal epilepsy | 238 (29%) | |
Symptomatic focal epilepsy | 416 (51%) | |
Idiopathic generalised epilepsy | 68 (8%) | |
Other epilepsy syndrome | 68 (8%) | |
Not classifiable | 21 (3%) | |
Age, years; mean (range) | 37 (14 to 79) | |
Sex (Female/Male) | 410/401 | |
Age at seizure onset, years; mean (range) | 11 (0 to 63) | |
With/without learning disability/not known | 164/493/154 | |
Maximum recorded daily dose, mg; mean (range) | 2267 (62.5* to 5000) | |
Treatment time, months; mean (range) | 16.7 (0 to 41) | |
Disposition: | ||
Continuing at last follow‐up | 528 (65%) | |
Stopped Lev | ||
Adverse events only | 81 (10%) | |
Inefficacy only | 110 (14%) | |
Adverse events and inefficacy | 75 (9%) | |
Pregnancy | 3 (0.4%) | |
Deceased | 7 (0.9%) | |
Unknown | 7 (0.9%) | |
Concurrent AEDs at start | ||
None | 39 (5%) | |
One | 253 (31%) | |
Two | 330 (41%) | |
Three | 151 (19%) | |
Four or more | 36 (4%) | |
Unknown | 2 (0.2%) |
*Quarter of a 250 mg tablet. Units are number (%) unless otherwise stated.