Table 1 Demographic and clinical data for the subject groups.
| Variable | Stable Parkinson's disease | Fluctuating Parkinson's disease | Parkinson's disease with dementia | Healthy controls |
|---|---|---|---|---|
| Number of subjects (M/F) | 47 (30/17) | 73 (40/33) | 39 (17/23) | 58 (29/29) |
| Age (years) | 62.0 (11.4) | 60.5 (8.2) | 68.6 (8.9) | 61.3 (11.0) |
| Education duration (years) | 11.89 (3.29) | 11.14 (2.95) | 8.79 (2.32) | 11.53 (2.97) |
| Mattis DRS score (max = 144) | 136.96 (4.60) | 134.33 (5.69) | 118.67 (7.84) | 138.27 (4.58) |
| MADRS score (max = 60) | 6.85 (6.09) | 9.76 (6.66) | 11.05 (6.17) | 4.57 (4.82) |
| UPDRS score (max = 108) | 15.53 (8.53) | 26.92 (12.56) | 32.46 (14.71) | NA |
| Dopa equivalent dosage (mg/day) | 711 (400) | 905 (506) | 912 (507) | NA |
Values are mean (SD).
DRS, dementia rating scale; F, female; M, male; MADRS, Montgomery and Asberg depression rating scale; NA, not available; UPDRS, Unified Parkinson's Disease Rating Scale.