Skip to main content
. 2006 May;77(5):665–667. doi: 10.1136/jnnp.2005.085019

Table 1 Studies examining the prevalence of the LRRK2 G2019S mutation in idiopathic PD cohorts.

Reference Case recruitment base Ethnicity PD cases Controls
Overall Familial Sporadic
n Carr Freq (%) n Carr Freq (%) n Carr Freq (%) n Carr
Aasly5 Outpatient clinic Norwegian 435 9 2.1 65 6 9.2 370 3 0.8 519 0
Berg6 N/A N/A 390 1 0.3 53 0 <1.8 337 1 0.3 1200 0
Bras7 Outpatient clinic Portugese 124 7 5.6 22 2 9.1 102 5 4.9 126 0
Deng8 N/A North American 326 4 1.2 150 3 2.0 176 1 0.6 130 0
Farrer9 Tertiary referral clinic North American 786 4 0.5 236 4 1.7 550 0 <0.2 278 0
Gilks10 Tertiary referral clinic White British 482 8 1.7 N/A 3 N/A N/A 5 N/A 345 0
Hernandez11 N/A Whiite North American 719 7 1.0 N/A 1 N/A N/A 6 N/A 2680 0
Kay12 Tertiary referral clinic North American (95% white) 1425 18 1.3 329 10 1.9 1096 8 0.7 1647 1
Zabetian13 Outpatient/research clinic North American (93% European) 371 3 0.8 74 1 1.4 297 2 0.7 281 0
Tan17 Tertiary referral clinic Asian† 675 0 <0.1 58 0 <1.7 617 0 <0.2 325 0
Skipper18 Tertiary referral clinic Asian‡ 630 0 <0.1 160* 0 <0.6 470 0 <0.2 630 0
Bialecka19 Outpatient clinic Polish 174 0 <0.5 21 0 <4.7 153 0 <0.7 190 0
This study Community/research clinic White British 519 2 0.4 74 1 1.4 445 1 0.2 887 0

*Non‐dominant family history; †88% Chinese, 7% Malay, 5% Indian; ‡84% Chinese, 8% Malay, 2% mixed Asian; Carr, carriers; Freq, frequency; N/A, not applicable.