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. 2007 Mar 12;78(10):1056–1063. doi: 10.1136/jnnp.2006.099424

Table 4 Cohen's D effect sizes for the ADAS‐cog and CIBIC‐Plus.

Week Rivastigmine TID vs placebo Rivastigmine BID vs placebo
D D
ADAS‐cog
 12 0.48 0.30
 18 0.52 0.30
 26 0.41 0.22
CIBIC‐Plus
 12 0.40 0.40
 18 0.54 0.36
 26 0.46 0.31

ADAS‐cog, cognitive subscale of the Alzheimer's Disease Assessment Scale; BID, twice daily; CIBIC‐Plus, Clinician Interview Based Impression of Change incorporating caregiver information; TID, three times daily.