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. 2007 Feb 7;78(11):1218–1225. doi: 10.1136/jnnp.2006.111716

Table 1 Important characteristics of the included studies.

Author Year subjects recruited Disease group* Imaging modality No of subjects (arteries) Prospective Consecutive Imaging technique stated Blind assessment of imaging Method of derivation of stenosis stated Vessel compared Degree of stenosis compared (%)
Ackerstaff 198415 1981–1982 E Duplex without colour 82 (103) No No Yes No‐Duplex Yes VAO 1–99, 100
Yes‐ IAA
Ackerstaff 198816 1983–1987 E Duplex without colour Nm (239) No No Yes Yes Yes VAO, V1 0–49, 50–99, 100
Visona 198625 1981–1983 B, C, D Duplex without colour 25 (30) Yes No No No Yes‐Duplex VAO 0, 50–99, 100
No‐IAA
De Bray 200119 1996–1998 A, B, D Colour duplex 158 (316) Yes Yes Yes Yes Yes‐Duplex ECVA 0, 1–29, 30–49, 50–69, 70–99, 100
No‐IAA
Harrer 200426 NM C, D 2D and 3D Colour duplex 6 (6) No No Yes Yes Yes VAO <30, 30–69, >70 (raw data)
Wentz 199427 NM E Non‐contrast MRA 60 (161) No No Yes Yes Yes ICVA and BA data merged 0, <50, 50–75, >75, 100
Strotzer 199823 NM E Non‐contrast MRA 40 (80) Yes Yes Yes Yes‐MRA No‐MRA VAO ⩾50
No‐IAA Yes‐IAA
Leclerc 199820 1997 A, B CE‐MRA 3D 27 (50) No No Yes Yes Yes ECVA 0, <50, 50–70, >70, 100
Randoux 200324 2000–2001 C CE‐MRA 33 (66) Yes Yes Yes Yes Yes VAO 0,<50, >50, 100
Cosottini 200321 NM A, B CE‐MRA 48 (89) Yes No Yes‐MRA Yes No ECVA 0, <30, 30–70, >70, 100
No‐IAA
Kim 200528 NM D, E CE‐MRA 37 (74) Yes No Yes‐ MRA No Yes ECVA >50, 100
No‐IAA
Yang 200517 2001–2002 A, B, E CE‐MRA 40 (unclear) No No Yes Yes Yes ECVA, ICVA, BA >50, 100
Farres 199622 NM A CTA 24 (44 for V1, 33 for V0) No No Yes No No V0, V1 (incomplete data for V0) <50, 50–70, >70, 100

BA, basilar artery; CE‐MRA, contrast enhanced magnetic resonance angiography; Consecutive, patients recruited consecutively into the study; CTA, computed tomographic angiography; ECVA, extracranial vertebral artery; IAA, intra‐arterial angiography; ICVA, intracranial vertebral artery; MRA, magnetic resonance angiography; NM, not mentioned; Prospective, prospective recruitment of patients; TIA, transient ischaemic attack; VAO, vertebral artery origin.

The number of vessels compared excludes the number of vessels not seen.

*Disease group: A = posterior circulation stroke or TIA, probably due to atheromatous disease; B = stroke or TIA, probably due to atheromatous disease (anterior circulation stroke or unspecified territory); C = risk factors for cerebrovascular disease; D = healthy individuals; E = other (including not mentioned, suspected atheromatous disease and neurological symptoms without stating vascular history).