Table 2 Sensitivity, specificity and diagnostic odds ratio for 70–99% stenosis, 50–59/70% stenosis, 50–99% stenosis and occlusion in all imaging groups.
| Imaging | No of studies* | No of arteries | Sensitivity (95% CI) | Specificity (95% CI) | DOR (95% CI) |
|---|---|---|---|---|---|
| 70–99% stenosis | |||||
| Colour duplex | 1 | 316 | 65.2 (42.7 to 83.6) | 99.3 (97.5 to 99.9) | 272.8 (53.2 to 1398.1) |
| CE‐MRA | 2 | 139 | 83.3 (35.9 to 99.6) | 98.5 (94.7 to 99.8) | 200 (22 to 1824) |
| CTA | 1 | 44 | 100 (2.5 to 100) | 100 (91.8 to 100) | 261 (3.7 to 18197) |
| 50–69/70% stenosis | |||||
| Colour duplex (50–69%) | 1 | 316 | 61.5 (31.6 to 86.1) | 98.7 (96.7 to 99.6) | 119.6 (26.9 to 531) |
| CE‐MRA (50–70%) | 1 | 50 | 50 (1.3 to 98.7) | 95.8 (85.7 to 99.5) | 23 (1 to 517) |
| CTA (50–70%) | 1 | 44 | 100 (2.5 to 100) | 95.3 (84.2 to 99.4) | 49.8 (1.69 to 1562.1) |
| 50–99% stenosis | |||||
| Duplex without colour | 2 | 269 | 70.2 (56.6 to 81.6) | 93.4 (89.2 to 96.3) | 37 (16 to 83) |
| Colour Duplex | 2 | 322 | 70.2 (54.2 to 83.3) | 97.7 (95.2 to 99.1)† | 75 (24 to 34) |
| TOF MRA | 2 | 224 | 71.4(47.8 to 88.7)† | 95.1 (91.1 to 97.6)† | 22 (7 to 64)† |
| CE‐MRA | 4 | 263 | 93.9 (79.8 to 99.3) | 94.8 (91.1 to 97.3)† | 179 (42 to 765) |
| CTA | 1 | 44 | 100 (15.8 to 100) | 95.2(83.8 to 99.4) | 81 (3 to 2183.3) |
| 100% (occlusion) | |||||
| Duplex without colour | 3 | 372 | 98.8 (89.4 to 100) | 90.8 (87.2 to 93.7)† | 211 (38 to 1172) |
| Colour Duplex | 1 | 316 | 83.3 (51.6 to 97.9) | 100 (98.8 to 100) | 2557.8 (115.4 to 56671) |
| TOF MRA | 1 | 161 | 100 (75.3 to 100) | 100 (97.5 to 100) | 8019 (153 to 420402) |
| CE‐MRA | 4 | 278 | 89.5 (66.9 to 98.7) | 99.6 (97.9 to 100) | 429.7 (73.9 to 2498.6) |
CE‐MRA, contrast enhanced magnetic resonance angiography; CTA, computed tomographic angiography; DOR, diagnostic odds ratio; MRA, magnetic resonance angiography; TOF, time of flight.
*Where more than one study is available the results have been pooled using the fixed effects model
†Significant heterogeneity (χ2 testing, p<0.05).