Table 1 Characteristics and primary causes of death.
MSA (n = 21) | PD (n = 21) | |
---|---|---|
Sex | 10M/11F | 10M/11F |
Mean (SD) age at disease onset (years) | 59.4 (10.1) | 59.9 (8.9) |
Mean (SD) disease duration (years)* | 8.5 (4.7) | 13.4 (8.2) |
MSA type at presentation (%) | ||
MSA‐P | 16 (76.2) | |
MSA‐C | 5 (23.8) | |
Permanent balloon (Foley) catheters (%)† | 15 (71.4) | 7 (33.3) |
Percutaneous gastrostomy (%) | 8 (38.1) | 3 (14.3) |
Tracheostomy (%) | 2 (9.5) | None |
Sudden death (%)‡ | 8 (38.1) | 3 (14.3) |
Cause of death (%) | ||
Cardiopulmonary arrest | 7 (33.3) | 1 (4.8) |
Urinary tract infection | 5 (23.8) | None |
Aspiration pneumonia | 2 (9.5) | None |
Infectious pneumonia | 2 (9.5) | 7 (33.3) |
Acute aspiration | 1 (4.8) | 1 (4.8) |
Wasting syndrome | 3 (14.3) | 1 (4.8) |
Cerebrovascular accident | None | 3 (14.3) |
Myocardial infarction | None | 2 (9.5) |
Cancer | None | 2 (9.5) |
Other | 1 (4.8) | 1 (4.8) |
F, female; M, male; MSA, multiple system atrophy; MSA‐C, MSA with a clinical predominance of cerebellar symptoms; MSA‐P; MSA with a clinical predominance of parkinsonism; PD, Parkinson's disease.
Results in the comparisons between MSA and PD groups were significant for *p = 0.02, †p = 0.03 and ‡p = 0.02.