Table 5 Comparison of clinical features and neuroimaging findings between bacterial brain abscesses with or without intraventricular rupture.

	Subsequent IVRBA n = 17	Without IVRBA n = 117	p Value	OR	95% CI
Sex (male/female)	13/4	91/26	1	1.08	0.32 to 3.58
Mean age (years)	46.8 (15.1)	43.8 (18.5)	0.468
Mental state at the time of admission
Clear consciousness (GCS = 15)	8	69	0.353	0.618	0.22 to 1.71
Disturbed consciousness (GCS<15)	9	48
Mean (SD) duration between onset of symptoms and diagnosis of abscess	10.4 (12.1)	15.2 (22.7)	0.518
Underlying diseases
Congenital heart disease	0	15	0.216	0.87	0.81 to 0.93
Diabetes mellitus	3	18	0.733	1.17	0.3 to 4.48
Alcoholism/liver cirrhosis	2	15	1	0.91	0.18 to 4.37
Chronic otitis media	1	15	0.692	0.43	0.05 to 3.44
Postneurosurgical state	6	30	0.394	1.582	0.54 to 4.65
Clinical features
Fever	12	65	0.241	1.92	0.64 to 5.8
Headache	7	65	0.267	0.56	0.2 to 1.57
Hemiparesis	8	54	0.944	1.04	0.37 to 2.87
Nausea/vomiting	6	25	0.224	2.01	0.68 to 5.96
Neck stiffness	2	31	0.24	0.37	0.08 to 1.71
Seizure	2	20	0.738	0.65	0.14 to 3.05
Hydrocephalus	4	13	0.232	2.46	0.7 to 8.68
Septic shock	1	11	1	0.6	0.07 to 4.99
Visual disturbance	1	20	0.472	0.3	0.04 to 2.42
Papilloedema	0	7	0.595	0.42	0.02 to 7.7
Hemiparesthesia	8	54	0.287	1.04	0.37 to 2.87
Associated with meningitis	7	37	0.433	1.51	0.53 to 4.29
Portal of entry
Haematogenous spread	6	34	0.6	1.332	0.46 to 3.89
Non‐haematogenous spread	11	83
Acquisition of infection
Nosocomially acquired	6	31	0.562	1.51	0.52 to 4.44
Community acquired	11	86
Neuroimaging findings
Mean (SD) nearest distance between the ventricular wall and margin of brain abscess	11.1 (10.1)	19.1 (9.7)	0.001
Mean (SD) size of the nearest brain abscess	31.2 (14.6)	34.5 (18.1)	0.571
Multiloculation	7	20	0.045	3.36	1.15 to 9.99
Mortality	5	32	1	1.11	0.36 to 3.39
Median (range) GOS at 3‐month end point	3 (1–5)	2 (1–5)	0.276

GCS, Glasgow Coma Score; GOS, Glasgow Outcome Score; IVRBA, intraventricular rupture of brain abscesses.