Table 1.
E. coli strain | FimH variant | M1:M3 ratio | Yeast cell agglutination† | Guinea pig RBC agglutination† | Buccal cell binding‡ | Uroplaque binding§ |
---|---|---|---|---|---|---|
KB91 | M1L | 0.08 | 16 | 2 | 185 ± 15 | 0.26 ± 0.05 |
KB96 | M1H | 0.63 | 16 | 16 | 194 ± 12 | 3.35 ± 0.15 |
Binding in all of these assays was inhibited more than 95% by 1% α-methyl-d-mannopyranoside.
Functionally, strains KB91 and KB96 are completely representative of other M1L and M1H phenotype strains.
Last dilution causing agglutination.
Buccal epithelial cells bound per well, mean ± standard error of mean.
E. coli bound (cfu per well × 106), mean ± standard error of mean.