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. 2006 Jun 26;78(1):25–29. doi: 10.1136/jnnp.2006.094342

Table 4 Differences in rates of cognitive deterioration between those taking and not taking antipsychotic drugs.

Cognitive test Deterioration Statistics 95% CI/IQR p Value
Taking antipsychotics Not taking antipsychotics
SIB, median (range) 3.0 (−34 to 32) 0 (−22 to 87) U = 1712.0 IQR−3–4 0.247
MMSE, mean (SD) 1.0 (3.1) 0.9 (3.6) t = −0.2 95% CI −1.4 to 1.2 0.878
ADAS‐cog, mean (SD) 2.8 (8.0) 1.4 (8.1) t = −0.8 95% CI −5.0 to 2.1 0.421

ADAS‐cog, Alzheimer's Disease Assessment Scale—Cognitive Subscale; IQR, interquartile range; MMSE, Mini‐Mental State Examination; SIB, severe impairment battery; t, T test; U, Mann–Whitney U test.