Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Jan 23;203(1):41–46. doi: 10.1084/jem.20051512

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 5. — APOBEC3G siRNA blocks IFN-α anti-HIV activity. Monocytes were transfected with APOBEC3G siRNA, cultured for 6 d, infected with HIV, and treated or not with 1 ng/ml IFN-α. P24 levels were monitored in the supernatants of untreated and treated macrophage cultures at the indicated time points after infection with HIV. Inset: Nested PCR to evaluate initial rounds of HIV replication (day 2 after infection) in cells transfected with APOBEC3G-specific siRNA or negative control siRNA, electroporation only control (EPC), or left untreated (C), and then infected with HIV. Increased proviral DNA was evident in cells depleted of APOBEC3G. Representative experiment, n = 3.