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TEC induces mitochondrial, but not nuclear, translocation of GR in TEC-sensitive PD1.6 cells. PD1.6, PD1.6TEC−, and GR-deficient PD1.6Dex− cells were incubated alone or with TEC for 4 h. Nonadherent lymphoma cells were harvested and subjected to subcellular fractionation and Western blotting. The samples were harvested at an early stage after cocultivation with TEC, long before the onset of the apoptotic process. Thus, CytoC could be used as a marker for the mitochondria.
