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. 2006 Oct 30;203(11):2425–2431. doi: 10.1084/jem.20061292

Table I.

Analysis of CSR on the t(14;18)+ translocated allele in peripheral blood from HI

Sample BCL2/JH a
BCL2/Sμ
BCL2/Sγ
Detection Ratio Frequency Detection Ratio Associated JH Detection Ratio Associated JH Isotype
99 yes 11:30 1.1 × 10−5 no 0:10 - yes 1:5 JH6* γ1
102 yes 23:30 3.6 × 10−5 yes 1:5 JH5 yes 1:5 JH5 γ1
103 yes 14:30 1.6 × 10−5 yes 1:10 JH6b no 0:10 - -
109 yes 12:30 1.3 × 10−5 no 0:10 - yes 1:10 JH? γ2
120 yes 11:30 1.1 × 10−5 no 0:10 - yes 2:10 JH4* γ1
127 yes 23:30 3.6 × 10−5 no 0:10 - yes 4:10 JH6* γ2
JH6* γ1
Mean 2.1 × 10−5
Total 6:6 2:6 2:55b 5:6 9:50b
a

Previously described in reference 8 Ratio, positive replicates:total replicates.

b

Cumulative occurrence of BCL2/Sμ junctions, as determined by the Pearson's χ2 test, was significantly lower than BCL2/Sγ junctions (P = 0.02).

*

BCL2/JH junction identical to the one previously found with the BCL2/JH PCR assay (8).