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. 2006 Nov 27;203(12):2715–2725. doi: 10.1084/jem.20061401

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Copyright © 2006, The Rockefeller University Press

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Figure 2. — IL-17 is induced in the lung upon allergen challenge. Mice were sensitized and challenged with OVA, and IL-17 and IL-23 were determined by ELISA in the lung homogenate (A and B). In naive, nonsensitized mice, no IL-17 was detected (A). In C and D, cells from mediastinal lymph nodes (MLNs) or splenocytes of sensitized and challenged mice were restimulated in vitro with 300 ng/ml IL-23. The bars represent the mean ± SD (n = 8 animals per group). n.d., not detected. *, P ≤ 0.05; dotted line indicates basal levels.

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