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. 2006 Nov 27;203(12):2715–2725. doi: 10.1084/jem.20061401

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Copyright © 2006, The Rockefeller University Press

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Figure 6. — IL-17 inhibits TARC and eotaxin production ex vivo in lung explants. Lung explants (A and C) and lung adherent cells (B and D) were prepared from OVA-sensitized and challenged animals. Cells were treated with saline, 50 μg/ml OVA alone, IL-17 alone, or OVA plus 30 ng/ml IL-17 for 24 h. The concentrations of TARC (A and B) and eotaxin (C and D) were measured by ELISA. In lung cell cultures of naive, nonsensitized mice no TARC was detected (A). The results represent the mean ± SD of 8 animals per group. n.d., not detected. *, P ≤ 0.05.

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