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. 2006 Nov 27;203(12):2715–2725. doi: 10.1084/jem.20061401

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Copyright © 2006, The Rockefeller University Press

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Figure 7. — IL-17 inhibits TARC production and OVA uptake in DCs. DCs (A and C) and macrophages (B) were differentiated in vitro from naive bone marrow–derived cells. Cells were treated with saline, IL-17 alone, 3 ng/ml TNF, or TNF with 30 ng/ml IL-17 for 24 h. The concentrations of TARC (A and B) were measured by ELISA. The results represent the mean ± SD of 8 animals per group. In C, uptake of 100 μg/ml OVA-FITC by DCs in the absence and presence of IL-17 (+IL-17) was analyzed by FACS. A histogram is shown in the left panel. The mean fluorescence intensity (MFI) thereof is given in the right hand panel. n.d., not detected. *, P ≤ 0.05.

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