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. 2006 Feb 20;203(2):425–435. doi: 10.1084/jem.20052148

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Copyright © 2006, The Rockefeller University Press

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Figure 6. — T cells from PAR₂ WT animals show greater proliferation and IFN- γ production. (A) Lymphocytes isolated from lymph nodes of MOG-immunized WT animals (n = 4) show higher [³H]thymidine incorporation after coculture with MOG-loaded irradiated splenocytes compared with lymphocytes from immunized littermate KO animals (n = 4). (B and C) CD3:CD4-immunopositive cells from WT animals show higher levels of IFN-γ production after coculture with MOG-loaded splenocytes compared with the same population in KO animals. Student's t test; *, P < 0.05. Error bars represent standard errors.