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. 2006 Feb 20;203(2):425–435. doi: 10.1084/jem.20052148

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Copyright © 2006, The Rockefeller University Press

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Figure 7. — PAR₂ expression is associated with greater CNS inflammatory gene expression during EAE induction. mRNA levels of (A) TNF-α, (B) iNOS, (C) IL-6, and (D) IFN-γ were significantly higher in the CNS of PAR₂ WT animals with EAE (n = 5) compared with their KO littermates with EAE (n = 5) and intact animals (n = 4) for each genotype. RFC, relative fold change. Tukey-Kramer Multiple Comparisons test; *, P < 0.05.