Table I.
Immunofluorescence titers in mice immunized with αDEC-CS antibody
| Primea | Boostb | Reciprocal IFA titerc |
|---|---|---|
| PBS | αDEC-CS | <600 |
| αDEC-CS+anti-CD40+poly I:C | αDEC-CS | 106,920 (±53,237) |
| anti-CD40+poly I:C | αDEC-CS | 900 (±600) |
| Irradiated sporozoites | — | 4,500 (±1,800) |
a
Groups of four mice were primed with 10 μg αDEC-CS plus maturation stimulus, maturation stimulus alone, 7.5 × 104 irradiated sporozoites, or PBS.
b
Mice were boosted with 10 μg αDEC-CS or nothing.
c
Immunofluorescence assay was performed 7 d after boost using serial dilutions of serum from individual mice. Results are depicted as the mean of reciprocal titers ±SD.