Figure 5.
NS genes contribute to lethality of VN1203 in ferrets but not in mice. Survival rate (A), and mean weight change ± SE (B) of ferrets inoculated with CH58 (n = 3), VN1203-CH58(NS) (n = 6), or CH58-VN1203(3P) (n = 3) reassortant virus. Survival rate (C) and mean weight change ± SE (D) of mice (n = 8) inoculated with CH58 (n = 8), VN1203-CH58(NS) (n = 8), or CH58-VN1203(3P) (n = 4).