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. 2006 Apr 17;203(4):1117–1127. doi: 10.1084/jem.20052321

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Copyright © 2006, The Rockefeller University Press

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Figure 6. — HO-1 is the molecular target for probucol and probucol dithiobisphenol. All animals (n = 6 per group) received tin(IV) protoporphyrin IX dichloride to block heme oxygenase. (A) Intima-to-media ratio of vessels 6 wk after aortic balloon injury (eight serial sections per segment, 100 μm apart). (B) Reendothelialization assessed by the length (mm) of section covered by CD-31⁺ cells from the branch orifice (three to six serial sections per segment, 100 μm apart), and (C) cell proliferation is indicated by PCNA⁺ cells 6 wk after injury. Symbols and abbreviations are as described in the legend to Fig. 1.