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CyP inhibits LPS-induced endotoxin shock in mice. (A) C57BL/6 mice were sensitized with d-galactosamine and injected i.p. with 25 ng S. abortus equi LPS alone (13 mice, ⋄) or in combination with 750 μg CyP (12 mice, •). (B) C57BL/6 mice were injected i.p. with 1.5 mg E. coli 055:B5 LPS alone (6 mice, ⋄) or in combination with 850 μg CyP (10 mice, •). p-values calculated by the Kaplan-Meyer log-rank test are indicated.
