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. 2006 Jul 10;203(7):1761–1772. doi: 10.1084/jem.20060075

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Copyright © 2006, The Rockefeller University Press

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Figure 4. — cGvH induces long-lasting activation of T cells in splenocytes of 56R mice. Expression of CD4, CD69, and the T cell costimulatory molecules CD28 and ICOS is shown on CD3⁺ T cells, and the expression of CD44 and CD45RB is shown on CD4⁺ T cells (dot plots). The levels of CD62L on CD4⁺ T cells (histograms) were decreased after cGvH (black line) as compared to the control (gray line) at days 14 and 60. One representative experiment out of five is shown.