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. 2006 Jul 10;203(7):1745–1759. doi: 10.1084/jem.20060085

Figure 5.

Figure 5.

IL-12 and IFN-γ production by leukocytes. Cytokine production by PBMCs from 10 healthy donors, (C+, •), P2 (□), and P3 (◯) in response to PHA, alone or in combination with recombinant IL-12 (20 ng/ml), IL-23 (20 ng/ml), or IFNγ (5,000 UI/ml), anti-CD3 (10 ng/ml), LPS (1 μg/ml) and PMA/ionomycin (10−7/10−5 M). (A) IFN-γ, (B) IL-12p70, (C) IL-12p40 production. (D) Cytokine production by whole blood cells from 50 healthy donors, P2, and P3 upon stimulation with live BCG alone or in combination with IL-12 (20 ng/ml) or IFN-γ (5,000 IU/ml): IFN-γ (top), IL-12p70 (middle), and IL-12p40 (bottom) secretion. For each patient, the results shown are representative of two independent experiments.